Analysis Note

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma

single band by SDS-PAGE

General description

Native coagulation factor XI from human plasma. Consists of two identical polypeptide chains linked by disulfide bonds, that yield a single band at 80,000 on reduction with β-mercaptoethanol. In vivo, Factor XI is activated to Factor XIa by Factor XIIa.

Native coagulation factor XI from human plasma. Consists of two identical polypeptide chains linked by disulfide bonds, that yield a single band at 80 kDa upon reduction with β-mercaptoethanol. In vivo, Factor XI is activated to Factor XIa by Factor XIIa.

Coagulation Factor XI, Human Plasma, CAS 9013-55-2, is a native coagulation factor XI with two identical polypeptide chains linked by disulfide bond. It is activated to Factor XIa by Factor XIIa.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Packaging

100 µg in Plastic ampoule

Please refer to vial label for lot-specific concentration.

Physical form

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Warning

Toxicity: Standard Handling (A)